NAYO was established in 2004 by four local youths to help other young people impacted by HIV/AIDS.
NAYO provides a holistic approach to youth and community development through a variety of interventions, including running an HIV testing, prevention, and treatment clinic as well as services to breastfeeding mothers and children under five.
They also provide educational support, lead youth clubs, and facilitate village savings and loan groups. Since its inception, NAYO has supported over 50,000 people in the Nancholi area of southern Malawi.